Rafael Márquez is preparing to manage his first match at the helm of the Mexican National Team this Saturday, September 26th, against Colombia in Baltimore, marking a new phase on the road to the next World Cup. However, the former defender's debut will be marked by several significant absences, after Raúl Jiménez and Julián Quiñones were ruled out before the official squad announcement, while Alan Cervantes and César Montes were later withdrawn due to physical issues.

Raúl Jiménez suffered an injury to his left knee during Wolverhampton's match against Everton and is expected to be sidelined for several weeks. Julián Quiñones, meanwhile, experienced a muscular discomfort with Al-Qadsiah and remained with his club to complete his recovery. They were joined by Alan Cervantes, who reported muscular discomfort after playing 52 minutes of the Clásico Nacional, and César Montes, who was diagnosed with a tear in his right glute and will return to Russia to continue his rehabilitation with Lokomotiv Moscow.

The situation also saw Santiago Giménez and Jeremy Márquez under observation, although both managed to continue with the group and traveled for the commitment against Colombia. Giménez had a right adductor overload, while Jeremy suffered a back strain; their conditions were monitored by the medical staff, and they ultimately remained available for the debut. In this way, Márquez will face his premiere with a squad that has undergone significant modifications since before his first call-up, with four confirmed absences and two players who overcame their respective discomforts.